David A. Grimes, M.D.
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Research interests

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Dr. Grimes has helped to introduce evidence-based medicine to American obstetrics and gynecology.  His research interests bridge the disciplines of clinical obstetrics and gynecology and public health.  His research over the past four decades has focused on fertility regulation, including contraception, abortion, and sterilization.  He has also contributed to the literature on sexually transmitted diseases and technology assessment. 

An expert in clinical research, he has published numerous articles on research methods; these include series on clinical research published in The Lancet in 2002 and in 2005.  This led to the publication in 2006 of The Lancet Handbook of Essential Concepts in Clinical Research.

Because of his expertise in evidence-based medicine, he served on the U.S. Preventive Services Task Force, and he has published numerous Cochrane systematic reviews of fertility regulation methods.